Those little webs suggest spider mites. I would spray with an insecticidal soap or a rose care product. Insecticidal soap is easy to make if you don't have a prepared product. Just mix one teaspoon of dish detergent in a gallon of water.
No problem! Those little specks at the base of the bud look like they might be aphids. You probably have both. I am plagued by both of them in early to mid-spring unless I treat/spray. The soap will work on the aphids too. Go git 'em ;)
The slightly out-of-focus insects at the base of the rose bud are aphids. Aphids grow quite rapidly and, in the manner of snakes and caterpillars, must shed their skins a few times in their development. That is what the 'white' creatures on the bud are...the skin that has been shed. A high pressure spray from a garden hose (not as strong as a pressure washer) will take care of the problem if done a couple of times a week. The water spraying will also help against spider mites.