The general consensus is you should not plant datura next to consumables. Datura is in the same family as Tomatoes and Potatoes, Solanaceae. I have never heard of anyone becoming sick from vegetables growing next or near them and have done extensive research considering your question. On the other hand, honey produced near Brugmansia and Datura has been found to contain the 3 primary drugs found in Datura and Brugmansia.
All parts of Datura/Brugmansia are poisonous. Roots, stems, leaves, flowers and seeds. They contain the drugs atropine, scopolamine, and hyoscyamine in varying concentrations.
I have never given Honey a thought. The man down the road keeps bees and I do buy his Honey. My yard is full to the brim with Brugs and Datura. Just how much of the toxins come thru in the honey? I have never noticed any strange affects but then I have no Idea what effect those drugs have on the body. Have there been any studys on this? Very curious now...
Some substances which are toxic to humans have no effect on bees. If bees obtain their nectar from certain flowers, the resulting honey can be psychoactive, or even toxic to humans, but innocuous to bees and bee larvae.
There have been famous episodes of inebriation of humans from consuming toxic honey throughout history. Xenophon, Aristotle, Strabo, Pliny the Elder and Columella all document the results of eating "maddening" honey. Honey from these plants poisoned Roman troops in the first century BCE under Pompey the Great when they were attacking the Heptakometes in Turkey. The soldiers were delirious and vomiting after eating the toxic honey. The Romans were easily defeated.
For example, honey produced from nectar of Rhododendron ponticum and Azalea pontica contain alkaloids that are poisonous to humans but do not harm bees. Honey produced from the nectar of andromeda flowers contains grayanotoxins which can paralyze the limbs, and eventually the diaphragm and result in death. Honey obtained from Kalmia latifolia, the calico bush, mountain laurel or spoon-wood of the northern United States, and allied species such as sheep laurel (Kalmia angustifolia) can produce sickness or even death. The nectar of the "wharangi bush", the Melicope ternata in New Zealand also produces toxic honey, and this has been fatal. The dangers of toxic honey were also well-known among the Pre-Columbian residents of the Yucutan Peninsula, though this was honey produced by stingless bees, not by honey bees, which are not native to the Americas. Bee nectar collection from Datura plants in Mexico and Hungary, belladonna flowers, henbane (Hyoscamus niger) plants from Hungary, Serjania lethalis from Brazil and Gelsemium sempervirens from the American Southwest can all result in toxic honey.
The most common symptoms of datura/brugmansia poisoning are blurred vision, agitation, pupil dilation, dry mouth and mild headaches. People react differently to the drugs and the dosage. Datura/brug poisoning usually occurs when you are cutting branches, pulling leaves or harvesting seeds. What happens is that you have cuts on your hands or fingers or touch your face or eat something. That is why it is important to always wash your hands after working with dats or brugs or wear gloves if you have cuts on your hands. Most people do not associate dat/brug poisoning with the above symptoms because they are mild and short lived. When I have been poisoned, its usually after harvesting datura seeds. I get the blurred vision and agitation. Rarely are the symptoms severe enough to require a hospital visit, but if they are severe enough, it is very important that you tell the nurse or physician that you have been handling datura or brugmansia.